Endocrine Abstracts

Introduction: Pituitary Stalk Interruption Syndrome (PSIS) is a distinct and rare clinical entity responsible for isolated or combined anterior pituitary insufficiency. The objective of this work is to describe the clinical, hormonal and radiological aspects of PSIS.Patients and methods: Observational descriptive study of the files of 5 patients including 4 cases of congenital PSIS and one acquired, followed in the endocrinology and diabetology departmen...

Introduction: Thyroid disorders are quite common during pregnancy complicated by diabetes mellitus.Objective: The aim of our study was to detect thyroid disorders in a group of diabetic pregnant women.Patients and methods: Rétrospective study involving 243 pregnant women with diabetes followed in consultation or hospitalized in Endocrinology and Diabetology department of Ibn Rochd University Hospital of Casablanca, over a peri...

Introduction: Grave’ disease is associated with extra thyroid auto-thyroid manifestations such as basal ophthalmopathy and/or. We report the case of two patients presenting with extrathyroid manifestations of the basic illness hospitalized at the department of diabetic endocrinology and metabolic diseases of Ibn Rochd University Hospital of Casablanca.Case 1: This is a patient aged 53 years, chronic smoking at 20 years, for low weight disease since ...

Background: The discovery of a thyroid nodule is a problem in thyroid cancer screening. Thus, the analysis of the criteria of malignancy remains the first step of study of a thyroid nodule. The objective of our study was the correlation between the clinical, ultrasonographic and cytologic malignancy criteria and the anatomopathological study results of the operative specimen.Materials and methods: For this we conducted an analytical cross-sectional study...

Introduction: Atypia of undetermined significance (AUS) or follicular lesion of undetermined significance (FLUS) of Bethesda system for reporting thyroid cytopathology has emerged as most controversial category due to its heterogeneity and inconsistent usage. Initially associated risk of malignancy was estimated to be about 5–15%, but eventually different results have been obtained across institutions due to variable follow-ups and interpretation. The objective of this st...

Introduction: Patients with hyperparathyroidism have impaired carbohydrate metabolism characterized by insulin resistance, hyperinsulinemia and glucose intolerance. The objective of our work was to evaluate the prevalence of different carbohydrate metabolism disorders in patients with hyperparathyroidism and the impact of parathyroidectomy in improving glycemic counts.Methods: Retrospective study conducted at the Department of Endocrinology Diabetology a...

Introduction: Pheochromocytoma is rarely associated with neurofibromatosis type 1 (NF1). We report 4 observations of hospitalized patients in theIbn Rochd University Hospital endocrinology department in Casablanca.Observation 1: A 52-year-old male patient was admitted for NF1-associated malignant pheochromocytomawith paroxysmal hypertension, Menard triad, elevated methoxylated urinary derivatives (DMU), and 11 * 8 cm right adrenal mass with hepatic metas...

Background: Osteoporosis is a not uncommon complication of endocrine disease. It may even be accompanied by endocrinopathy. The aim of study was to determine mineral bone density profile of patients with endocrinopathy and define the osteoporosis and osteopenia prevalence in these patients.Materials and methods: Descriptive study included 177 patients followed for endocrinopathy (hypercorticism, hyperparathyroidism, prolactinoma and hypogonadism) in Endo...

Background: Many endocrine diseases can be complicated by diabetes, due to hyperglycemic hormones and insulinresistance. The aim of the work was to analyze prevalence, therapeutic and progressive aspects of secondary diabetes as well as carbohydrate intolerance (CHI) in patients with an endocrinopathy.Materials and methods: A retrospective study was conducted in the endocrinology and diabetology department including 161 patients followed for diabetes or ...

Introduction: Pregnancy in women with diabetes is considered high risk because of potentially serious maternal and fetal complications that can put in to risk the maternal and fetal prognosis.Objective: Describe and analyze risks associated with diabetic pregnancies and compare maternal fetal prognosis of pregnancies with pregestational diabetes (T1D and T2D) with gestational diabetes mellitus (GDM).Patients and methods: It was a d...